Process analytical technology for high shear wet Granulation
Microbioz India, August, 2018 Issue
Cover Story : “Process analytical technology for high shear wet Granulation"
Volume : 4 issue 8
Dear friends and readers, I hope you would have enjoyed reading our previous issue. Once again, I am delighted to bring for you the new edition of your favourite magazine Microbioz India. It is a “Laboratory Edition” supported by the cover story titled ‘Process Analytical Technology for High Shear Wet Granulation’ by Tim Freeman, Managing Director, Freeman Technology Ltd
High shear wet granulation (HSWG) transforms fine powder blends into free-flowing granules with improved compression properties during the tabletting process. Granulation also enhances the uniformity of a blend, increases density and reduces dust levels, an important health and safety benefit. The pharmaceutical industry is one of several which rely heavily on HSWG processes, most especially in the manufacture of oral solid dosage forms.
A Quality-by-Design (QbD) approach in drug development and manufacture relies on data collection at relevant points in the process to control the critical quality attributes (CQAs) of the product.
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