Pathogen Protection Capacity Of Fish By Itself May Help In Vaccine Development For Aquaculture Sectors

Pathogen Protection Capacity Of Fish By Itself May Help In Vaccine Development For Aquaculture Sectors

Overview

  • Post By : Microbioz India
  • Source: University of Pennsylvania
  • Date: 24 February, 2016

Researcher from University of Pennsylvania recently suggested that gills of fishes able to protect fish from number of disease causing pathogens in water. Fish induces number of protective antibody in its gills which helps in protection and which in returns may greatly support in development of vaccine for aquaculture sectors.

The study recently appears in journal Nature Communications. Researchers are now thinking this is how great interesting that fish able to detect harmful on its mucosal surfaces.

On the other hand scientists also finds the presence of antibodies named Immunoglobulin Ig T coated over mucosal surface helps in immune response .The antibody first discovered in Sunyer's lab in 2010 (Lead author of concern research too) ,before this study it was well known that only mammals can perform such a localized immune response.

According to Research:

"Our work is the first to show that fish can mount a local antibody response to pathogens and microbiota within a mucosal respiratory surface," Sunyer said. "We might expect that mucosal immunoglobulins play a key role in controlling the microbiota in mammals' lungs as well, which is something that has yet to be explored."

Note: The above story is only for information purposes for more information go through story source.

Story Source: University of Pennsylvania

Journal References

Zhen Xu, Fumio Takizawa, David Parra, Daniela Gómez, Louise von Gersdorff Jørgensen, Scott E. LaPatra, J. Oriol Sunyer. Mucosal immunoglobulins at respiratory surfaces mark an ancient association that predates the emergence of tetrapods. Nature Communications, 2016; 7: 10728 DOI: 10.1038/ncomms10728

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